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Sodium valproate

Published
Topics: Mental health and illnessNeurological disordersSafety in Breastfeeding · Sodium valproateStability in dosette boxes ·
Contents
  1. dm+d
  2. Articles
  3. Medicine Compliance Aid Stability
    1. Epilim · Sanofi
    2. Episenta · Desitin
    3. generic · Non-proprietary
    4. Epilim Chrono · Sanofi
    5. Epilim · Sanofi-Aventis
  4. Lactation Safety Information
    1. For bipolar disorder
    2. Oral / parenteral · for epilepsy

dm+d

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Articles

Specific medicine switches for solid dose and liquid formulations

13 September 2023

Valproic acid and Sodium valproate monitoring

15 July 2021

The Use of Generic Anti Epileptics Drugs in Patients with Epilepsy

28 September 2020Consensus views of the Pharmaceutical Market Support Group and the UK Clinical Pharmacists Association: Neurosciences Group on the safety and appropriateness of switching between brand…
Search Articles

Medicine Compliance Aid Stability

EpilimSanofi

Sanofi
Epilim
Tablets crushable 100mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from moisture
Company info - if benefit outweighs risk, repackage weekly not monthly and protect from moisture and humidity.
2 March 2015
Usage of Medicines in Compliance Aids

EpisentaDesitin

Desitin
Episenta
Capsules m/r 150mg, 300mg
R2 · Red 2Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Unsuitable for MCA as preparations are hygroscopic which can affect release profile.
25 October 2022
Usage of Medicines in Compliance Aids

genericNon-proprietary

Non-proprietary
generic
Tablets e/c 200mg, 500mg
R2 · Red 2Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Unsuitable for MCA as preparations are hygroscopic which can affect release profile.
25 October 2022
Usage of Medicines in Compliance Aids

Epilim ChronoSanofi

Sanofi
Epilim Chrono
Tablets m/r 200mg, 300mg, 500mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from moisture
Company info - if benefit outweighs risk, repackage weekly not monthly and protect from moisture and humidity.
2 March 2015
Usage of Medicines in Compliance Aids

EpilimSanofi-Aventis

Sanofi-Aventis
Epilim
Tablets e/c 200mg, 500mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Unsuitable
Company info - if benefit outweighs risk, repackage weekly not monthly and protect from moisture and humidity.
2 March 2015
Usage of Medicines in Compliance Aids

Lactation Safety Information

For bipolar disorder

For bipolar disorder
Caution
Carbamazepine; Appropriate second generation antipsychotic
Significant published evidence of safety in breastfeeding indicates small amounts in breast milk
Monitor infant for jaundice, bruising, and bleeding
MHRA states that it should not used in women of child bearing age unless Pregnancy Prevention Programme is in place, and only if other treatments are ineffective or not tolerated. For this reason, carbamazepine is preferred first-line in breastfeeding (see summary)
Safety in Lactation: Drugs for bipolar disorder and hypomania
26 July 2021
Bibliography

Oral / parenteral for epilepsy

Oral / parenteral
for epilepsy
Caution
Suitable alternative antiepileptic
Significant published evidence of safety in breastfeeding indicates small amounts in breast milk
Monitor infant for jaundice, bruising, and bleeding
Used in full-term neonates from birth
MHRA states that it should not used in women of child bearing age unless Pregnancy Prevention Programme is in place, and only if other treatments are ineffective or not tolerated (see summary).
Safety in Lactation: Control of epilepsy
26 July 2021
Bibliography