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Using certain antidepressants during breastfeeding
15 November 2023
Managing specific interactions with smoking
31 October 2023
Treating urinary disorders during breastfeeding
21 March 2023Oxybutynin is preferred for urinary frequency, enuresis, and incontinence during breastfeeding. Recommendations apply to full term and healthy infants only.
SNRIs to other antidepressants: switching in adults
17 February 2023How to switch safely between serotonin and noradrenaline reuptake inhibitors (SNRIs) or to other antidepressants. Seek specialist advice for complex switches.
Choosing an antidepressant for people with coronary heart disease
2 July 2021Prescribers may need to choose a safe antidepressant in people with CHD. We guide on available options. We do not cover management of complex depression.
Medicine Compliance Aid Stability
CymbaltaEli Lilly and Co Ltd
Eli Lilly and Co Ltd
Cymbalta
Capsules 30mg, 60mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Protect from moisture
Protect from moisture. Store in airtight container
15 November 2022
YentreveEli Lilly and Co Ltd
Eli Lilly and Co Ltd
Yentreve
Capsules 20mg, 40mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Protect from moisture
Protect from moisture. Store in airtight container.
22 December 2022
genericDr Reddy's Laboratories (UK) Ltd
Dr Reddy's Laboratories (UK) Ltd
generic
Capsules 30mg, 60mg
G2 · Green 2No stability data is available, but manufacturer suggests it is suitable for use in CAs.
Airtight container
Protect from moisture
Store in airtight container. Protect from moisture. Max 28 days in MCA.
2 August 2022
Lactation Safety Information
For depression
For depression
TCA: imipramine/nortriptyline SSRI: paroxetine/sertraline
Limited published evidence of safety
Small amounts found in breast milk that are likely to be degraded in infant’s GI tract, although relatively long half life increases risk of accumulation in breastfed infants
Monitor infant for drowsiness, poor feeding, irritability/behavioural effects
17 September 2018
For urinary incontinence
For urinary incontinence
Limited published evidence of safety
Small amounts in breast milk that are likely to be degraded in infant’s GI tract, although long half life increases risk of accumulation in breast fed infants
Monitor infant for drowsiness, poor feeding, irritability/ behavioural effects
17 September 2018