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Tricyclics to other antidepressants: switching in adults

17 February 2023How to switch safely between tricyclic antidepressants (TCAs) to other antidepressants or another TCA. Seek specialist advice for complex switches.

Choosing an antidepressant for people with coronary heart disease

2 July 2021Prescribers may need to choose a safe antidepressant in people with CHD. We guide on available options. We do not cover management of complex depression.
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Medicine Compliance Aid Stability

SinepinMarlborough Pharmaceuticals Ltd

Marlborough Pharmaceuticals Ltd
Sinepin
Capsules 25mg, 50mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Protect from light
Protect from light. Store in airtight containers
15 November 2022

Lactation Safety Information

Topical for pruritus

Topical
for pruritus
Calamine, Crotamiton
No published evidence of safety
Serious adverse effects reported in breastfed infant after oral doxepin
Risk from topical application cannot be excluded due to possible significant systemic absorption by the mother
Avoid use where possible
If use is clinically justified, do not apply to any part of the breast
30 October 2020