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Articles
Managing specific interactions with smoking
31 October 2023
Managing constipation in people taking clozapine
14 October 2022Constipation in people taking clozapine can be fatal. Guidance on preventing and managing constipation in these individuals is described.
Medicine Compliance Aid Stability
DenzapineBritannia Pharmaceuticals Ltd
Britannia Pharmaceuticals Ltd
Denzapine
Tablets 25mg, 50mg, 100mg, 200mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Protect from light
Protect from light. Sensitive to oxygen. Max 28 days in MCA.
7 November 2022
ClozarilMylan
Mylan
Clozaril
Tablets 25mg, 100mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Max 28 days in MCA. Sensitive to oxygen.
9 November 2022
ZaponexLeyden Delta BV
Leyden Delta BV
Zaponex
Tablets 25mg, 100mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Max 28 days in MCA. Sensitive to oxygen.
7 November 2022
Lactation Safety Information
Quetiapine, Haloperidol
Limited data suggest that clozapine may accumulate in breast milk
Agranulocytosis and delayed speech reported in breastfed infants
9 November 2018