Licensed for intrathecal use

Products licensed for intrathecal use are the first line option and should be used wherever suitable.

There are currently no known hydromorphone products licensed for intrathecal administration.

Not licensed for intrathecal use, limited information available

Products with partial information that are not licensed for intrathecal administration can still sometimes be used. Refer to the advice in our article and complete a risk assessment to enable you to interpret the details below and choose an appropriate product.

Napp (Palladone^®)

Strength

2mg/mL in 1mL ampoule
10mg/mL in 1mL ampoule

Excipients

Citric acid anhydrous, sodium citrate, sodium chloride, sodium hydroxide solution 4% (for pH adjustment), hydrochloric acid 3.6% (for pH adjustment), water for injection

Osmolarity

approx. 287 mOsmol/kg (undiluted)

pH

3.5 – 4.5 (undiluted)

Endotoxin content

≤ 84 EU/mL