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Switching between aminophylline and theophylline in adults

19 April 2022Intravenous aminophylline is used acutely for emergency respiratory conditions and we give a stepped approach on how to switch to oral theophylline

How should medicines be dosed in children who are obese?

28 May 2021Review on how to calculate medicine doses in children who are obese which includes a table on commonly prescribed medicines.
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Lactation Safety Information

Salbutamol; Terbutaline
Xanthine bronchodilator - mixture of theophylline and ethylenediamine
Limited published evidence of safety
Irritability and fretful sleep reported in one breastfed infant
Adverse effects potentially more likely in premature and newborn infants [due to slow elimination and low protein binding]
Modified-release products are preferred to parenteral formulations
Avoid feeding for 2 hours after IV dose
Monitor infant for irritability
Used in infants >1 month
29 July 2020