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SNRIs to other antidepressants: switching in adults

17 February 2023How to switch safely between serotonin and noradrenaline reuptake inhibitors (SNRIs) or to other antidepressants. Seek specialist advice for complex switches.

Choosing an antidepressant for people with coronary heart disease

2 July 2021Prescribers may need to choose a safe antidepressant in people with CHD. We guide on available options. We do not cover management of complex depression.
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Medicine Compliance Aid Stability

genericAccord Healthcare Limited

Accord Healthcare Limited
generic
Tablets f/c 37.5mg, 75mg, 150mg
A2 · Amber 2No stability data is available, the manufacturer does not, or cannot recommend use in CAs but there are no theoretical concerns with the product.
No special precautions for storage
No special precautions for storage.
7 December 2022

Polotid XLAccord UK Ltd

Accord UK Ltd
Polotid XL
Capsules m/r 37.5mg, 75mg, 150mg
A2 · Amber 2No stability data is available, the manufacturer does not, or cannot recommend use in CAs but there are no theoretical concerns with the product.
No special precautions for storage
No special precautions for storage
22 November 2022

Efexor XLUpjohn UK Limited

Upjohn UK Limited
Efexor XL
Capsules m/r 75mg, 150mg
A2 · Amber 2No stability data is available, the manufacturer does not, or cannot recommend use in CAs but there are no theoretical concerns with the product.
No special precautions for storage
No special precautions for storage
22 November 2022

Venlalic XLMartindale Pharma, an Ethypharm Group Company

Martindale Pharma, an Ethypharm Group Company
Venlalic XL
Tablets m/r 37.5mg, 75mg, 150mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from moisture
Protect from moisture. Max 7 days in MCA.
22 November 2022

Lactation Safety Information

TCA: imipramine/nortriptyline SSRI: paroxetine/sertraline
Moderate level of published evidence of safety in breastfeeding
Minor adverse effects reported in a small number of breastfed infants
Monitor infant for drowsiness, poor feeding, irritability/behavioural effects
16 September 2019