The first stop for professional medicines advice

Hydrocortisone

Published
Topics: Ear, nose and throat disordersEndocrine system disordersHydrocortisone · New MedicinesNHS England commissioned new medicinesSafety in BreastfeedingSkin disordersStability in dosette boxesStability outside the fridge ·
Contents
  1. dm+d
  2. Articles
  3. Refrigerated Storage
    1. Timodine · Alliance Pharmaceuticals
    2. Hydrocortisone · Colonis Pharma
  4. Medicine Compliance Aid Stability
    1. generic · Accord-UK Ltd
    2. Plenadren · ViroPharma Ltd
    3. Non-proprietary · Accord-UK Ltd
  5. Lactation Safety Information
    1. Oral / parenteral
    2. Local injection
    3. In the ear
    4. Orophayngeal - · buccal tablets
    5. Topical
    6. Rectal · for inflammatory bowel disease

dm+d

16602005

Articles

Switching between oral prednisolone and IV hydrocortisone

29 September 2023

Using oral or parenteral corticosteroids during breastfeeding

17 July 2023

Using inhaled or topical corticosteroids during breastfeeding

17 July 2023

Hydrocortisone: informing intrathecal risk assessment

11 August 2022Hydrocortisone products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration

Hydrocortisone acetate: informing intrathecal risk assessment

11 August 2022Hydrocortisone acetate products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration
Search Articles

Refrigerated Storage

TimodineAlliance Pharmaceuticals

Alliance Pharmaceuticals
Timodine
Cream (contains nystatin, dimeticone, hydrocortisone and benzalkonium chloride)

Contact Alliance Pharmaceuticals in all cases where a deviation from the recommended storage conditions has occurred. Refer to the current BNF for company contact details.
Please also refer to the manufacturer’s product literature for recommended storage information at https://www.medicines.org.uk

19 March 2021
London MI Service

HydrocortisoneColonis Pharma

Colonis Pharma
Hydrocortisone
Oral solution (5mg/5mL, 10mg/5mL)

Contact Colonis Pharma in all cases where a deviation from the recommended storage conditions has occurred.

Refer to the electronic medicines compendium (eMC) at https://www.medicines.org.uk for company contact details.

13 October 2022
London MI Service

Medicine Compliance Aid Stability

genericAccord-UK Ltd

Accord-UK Ltd
generic
Tablets 10mg, 20mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Store in airtight containers.
20 December 2022
Usage of Medicines in Compliance Aids

PlenadrenViroPharma Ltd

ViroPharma Ltd
Plenadren
Tablets m/r 5mg, 20mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Store in airtight containers.
22 November 2022
Usage of Medicines in Compliance Aids

Non-proprietaryAccord-UK Ltd

Accord-UK Ltd
Non-proprietary
Tablets mucoadhesive buccal 2.5mg
R2 · Red 2Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Mucoadhesive buccal tablets.
20 December 2022
Usage of Medicines in Compliance Aids

Lactation Safety Information

Oral / parenteral

Oral / parenteral
Yes
No published evidence of safety
Normal component of breast-milk
Used in full-term neonates from birth
Doses up to 160mg daily unlikely to cause adverse effects in the infant
Safety in Lactation: Corticosteroids
9 November 2020

Local injection

Local injection
Yes
11 September 2020

In the ear

In the ear
Yes
Only available in combination with gentamicin for which there are no additional risks
Safety in Lactation: Drugs for otitis externa
11 September 2020

Orophayngeal - buccal tablets

Orophayngeal -
buccal tablets
Yes
Safety in Lactation: Drugs for oral ulceration and inflammation
11 September 2020

Topical

Topical
Yes
Low potency
There are no additional risks when used in combination topical preparations containing antimicrobials or urea
Safety in Lactation: Topical corticosteroids
11 September 2020
LactMed

Rectal for inflammatory bowel disease

Rectal
for inflammatory bowel disease
Yes
-
No published evidence of safety after rectal administration
Small amounts in breast milk after oral administration
Doses up to 50mg orally daily unlikely to cause adverse effects in the infant
Safety in lactation: Drugs for chronic bowel disorders
11 September 2020
Bibliography