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Using vaccines during breastfeeding
Refrigerated Storage
Prevenar 13
PfizerIn the event of an inadvertent temperature excursion the following data may be used:
Prevenar 13 is licensed for storage at temperatures up to 25°C for four days. At the end of this period, any unused Prevenar 13 should be discarded.
In-house stability data shows Prevenar 13 may be exposed to temporary elevated temperature excursions (such as a refrigerator malfunction) of up to 25°C for a cumulative period of up to 7 days.
Public Health England has guidance on responding to errors in vaccine storage, handling and administration.
Pneumovax 23
Merck Sharp & Dohme LimitedContact MSD in all cases where a deviation from the recommended storage conditions has occurred. Refer to the electronic medicines compendium (eMC) at https://www.medicines.org.uk for company contact details.
Public Health England has guidance on responding to errors in vaccine storage, handling and administration.
Apexxnar
PfizerIn the event of an inadvertent temperature excursion the following data may be used:
Apexxnar is stable for 96 hours when stored at temperatures from 8°C to 25°C. At the end of this period Apexxnar should be used or discarded.
The vaccine is also stable when exposed for a cumulative storage at 25 ºC ± 2 ºC for 9 days after which the vaccine was returned to licensed storage conditions through its remaining shelf life.
A single excursion of 40 ± 2ºC is allowed for up to 14 days. Once an exposure has occurred, there is no information regarding returning the vaccine to the fridge in this case.
Please also refer to the manufacturer’s product literature for recommended storage information at https://www.medicines.org.uk
UK Security Health Agency has guidance on responding to errors in vaccine storage, handling and administration.
Vaxneuvance
MSDIn the event of an inadvertent temperature excursion the following data may be used:
Stability data indicate that Vaxneuvance is stable at temperatures up to 25°C for 48 hours.
Please also refer to the manufacturer’s product literature for recommended storage information at https://www.medicines.org.uk