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Choosing equivalent doses of oral benzodiazepines

25 January 2022Approximate equivalent doses of oral benzodiazepines to diazepam. Doses are not exact because of differences between the medicines.
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Refrigerated Storage

Lorazepam Macure Macure Pharma

Macure Pharma
Lorazepam Macure
4 mg/mL solution for injection

In the event of an inadvertent temperature excursion the following data may be used:
The product is stable when exposed to the following conditions:

  • 48 hours at temperatures up to 25°C.
  • 3 repeated excursions of 24 hours at 25°C.
  • 7 days at freezing temperatures.

The product can be returned to the fridge and no change in expiry date is required if exposed to the conditions above.

Please also refer to the manufacturer’s product literature for recommended storage information at https://www.medicines.org.uk.

17 August 2022
London MI Service

Medicine Compliance Aid Stability

genericGenus Pharmaceuticals

Genus Pharmaceuticals
generic
Tablets 1mg, 2.5mg
A3 · Amber 3No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Airtight container
Protect from light
Protect from moisture
Protect from moisture. Protect from light. Airtight container.
15 August 2022

Lactation Safety Information

For anxiety

For anxiety
Oxazepam
Shorter-acting agent
Limited published evidence of safety
Small amounts in breast milk
Monitor the infant closely for drowsiness, poor feeding and adequate weight gain
11 September 2020

Parenteral for status epilepticus

Parenteral
for status epilepticus
Clonazepam
Limited published evidence of safety
Small amounts in breast milk
Short-term therapy (1-2 doses) considered not to pose a risk to the infant
11 September 2020

For premedication / conscious sedation

For premedication / conscious sedation
Yes
Limited published evidence of safety
Small amounts in breast milk
Shorter-acting benzodiazepine
11 September 2020